Intraplatelet Calcium Signaling Regulates Thrombus Growth under Flow: Insights from a Multiscale Model
In injured arteries, platelets adhere to the subendothelium and initiate the coagulation process.They recruit other platelets and form a plug that stops blood leakage.The formation of the platelet plug depends on platelet activation, a process that is regulated by intracellular calcium signaling.Using an improved version of a previous multiscale mo